Publications

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Nault, R., Fader, K. A., Lydic, T. A. and Zacharewski, T. R. (2017). Lipidomic Evaluation of Aryl Hydrocarbon Receptor-Mediated Hepatic Steatosis in Male and Female Mice Elicited by 2,3,7,8-Tetrachlorodibenzo-p-dioxin. Chemical research in toxicology 30(4), 1060-1075. PMID: 28238261

Fader, K. A., Nault, R., Kirby, M. P., Markous, G., Matthews, J. and Zacharewski, T. R. (2017). Convergence of hepcidin deficiency, systemic iron overloading, heme accumulation, and REV-ERBalpha/beta activation in aryl hydrocarbon receptor-elicited hepatotoxicity. Toxicol Appl Pharmacol 321, 1-17. PMID: 28213091

Nault, R., Fader, K. A., Kopec, A. K., Harkema, J. R., Zacharewski, T. R. and Luyendyk, J. P. (2016). From the Cover: Coagulation-Driven Hepatic Fibrosis Requires Protease Activated Receptor-1 (PAR-1) in a Mouse Model of TCDD-Elicited Steatohepatitis. Toxicol Sci 154(2), 381-391. PMID: 27613713

Nault, R., Fader, K. A., Kirby, M. P., Ahmed, S., Matthews, J., Jones, A. D., Lunt, S. Y. and Zacharewski, T. R. (2016). Pyruvate Kinase Isoform Switching and Hepatic Metabolic Reprogramming by the Environmental Contaminant 2,3,7,8-Tetrachlorodibenzo-p-Dioxin. Toxicol Sci 149(2), 358-71. PMID: 26582802 supplementary data

Nault, R., Fader, K. A., Ammendolia, D. A., Dornbos, P., Potter, D., Sharratt, B., Kumagai, K., Harkema, J. R., Lunt, S. Y., Matthews, J. and Zacharewski, T. (2016). Dose-Dependent Metabolic Reprogramming and Differential Gene Expression in TCDD-Elicited Hepatic Fibrosis. Toxicol Sci 154(2), 253-266. PMID: 27562557

Nault, R., Fader, K. A. and Zacharewski, T. (2015). RNA-Seq versus oligonucleotide array assessment of dose-dependent TCDD-elicited hepatic gene expression in mice. BMC genomics 16(1), 373. PMID: 25958198

Nault, R., Colbry, D., Brandenberger, C., Harkema, J. R. and Zacharewski, T. R. (2015). Development of a computational high-throughput tool for the quantitative examination of dose-dependent histological features. Toxicol Pathol 43(3), 366-75. PMID: 25274660

Fader, K. A., Nault, R., Ammendolia, D. A., Harkema, J. R., Williams, K. J., Crawford, R. B., Kaminski, N. E., Potter, D., Sharratt, B. and Zacharewski, T. R. (2015). 2,3,7,8-Tetrachlorodibenzo-p-Dioxin Alters Lipid Metabolism and Depletes Immune Cell Populations in the Jejunum of C57BL/6 Mice. Toxicol Sci 148(2), 567-80. PMID: 26377647

Nault, R., Kim, S. and Zacharewski, T. R. (2013). Comparison of TCDD-elicited genome-wide hepatic gene expression in Sprague-Dawley rats and C57BL/6 mice. Toxicol Appl Pharmacol 267(2), 184-91. PMID: 23238561

Nault, R., Forgacs, A. L., Dere, E. and Zacharewski, T. R. (2013). Comparisons of differential gene expression elicited by TCDD, PCB126, betaNF, or ICZ in mouse hepatoma Hepa1c1c7 cells and C57BL/6 mouse liver. Toxicology letters 223(1), 52-59. PMID: 23994337

Kopec, A. K., Boverhof, D. R., Nault, R., Harkema, J. R., Tashiro, C., Potter, D., Sharratt, B., Chittim, B. and Zacharewski, T. R. (2013). Toxicogenomic Evaluation of Long-term Hepatic Effects of TCDD in Immature, Ovariectomized C57BL/6 Mice. Toxicol Sci 135(2), 465-75. PMID: 23864506